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 Energy expenditure can be directly measured using Oxygen consumption and C02 production and indirectly estimated by measuring of the heart rate?  

That's Correct!
It's Wrong!

Oxygen consumption and CO2 production are direct measures of energy expenditure because they reflect the amount of oxygen consumed and carbon dioxide produced during metabolism. Measuring heart rate is an indirect method of estimating energy expenditure because heart rate increases as the body requires more energy. Therefore, it is true that energy expenditure can be directly measured using oxygen consumption and CO2 production, and indirectly estimated by measuring heart rate.

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